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Il y a un demi siècle seulement, l'ADN livrait le secret de sa structure en double hélice. Depuis, il est devenu possible d'accéder aux mécanismes moléculaires de l'hérédité, de modifier les formes naturelles du vivant, et de créer des "OGM", des organismes génétiquement modifiés, bactéries, plantes ou animaux - sans que les processus biologiques mis en jeu soient toujours parfaitement compris, ni parfaitement maîtrisés. Les utilisations de la génétique réveillent dès lors des craintes anciennes, et en activent de nouvelles, qui touchent les unes et les autres aux conséquences de la manipulation du vivant, en général et de la modification de l'humain, en particulier. Ce livre analyse la manière dont notre société a accueilli ces techniques, et restitue les termes du débat qui en est résulté, pour aboutir à un constat implacable : jamais ce débat n'a été à la hauteur des enjeux. Fondé sur des recherches systématiques et précises, conjuguant clarté et rigueur scientifique, toujours très documenté, cet ouvrage mobilise sociologie, politologie et sciences juridiques de manière intégrée, refuse les facilités de la simple juxtaposition des perspectives offertes et dénonce la confiscation de thèmes scientifiques et techniques par les "experts". Par les analyses qu'il développe, ce livre constitue un plaidoyer argumenté pour une démocratie scientifique.
WB 60 Bioethics. Clinical ethics. Clinical ethics committees --- WB 60 Bioethics. Clinical ethics. Clinical ethics committees --- WB 60 Bioethics. Clinical ethics. Clinical ethics committees --- Genetic Engineering --- Genetic Engineering --- Genetic Engineering --- Social Values --- Social Values --- Social Values --- France --- France --- France --- Biotechnology --- Biotechnology --- Biotechnology
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Choosing a medical device is complex and requires a transparent process based on reason, evidence and assessment of prioritized public health needs. Poor choices lead to inappropriate use or non-use of medical devices and a waste of resources. This report suggests how an agenda to improve access to appropriate medical devices could be devised from applying the crucial 4 components - Availability, Accessibility, Appropriateness, and Affordability, to the 15 global high-burden diseases and some cross-cutting issues. The results of this exercise suggest several areas of research necessary to help make medical devices more available, accessible, appropriate, and affordable.Examples include: development of a kit containing simple and affordable technologies for measuring blood pressure, blood glucose and cholesterol levels, which could assess cardiovascular risk; developing portable, affordable spirometry equipment for accurate diagnosis and prognosis of chronic obstructive pulmonary disease (COPD) or asthma in low-resource settings; and the development of more appropriate hearing aids which could potentially help people with hearing impairments whatever their age or setting. An example of a key cross-cutting issue is the need to develop simple, affordable, and reliable sensitivity tests for bacterial and viral antigens. Such tests could replace culture systems to detect the presence of pathogens and effectively and efficiently help to diagnose many high-burden infections and neglected tropical diseases.The Priority Medical Devices (PMD) project applied the "4 A" questions to some examples of identified key medical devices to further explore the downstream issues associated with poor access to appropriate medical devices.The PMD project hopes all players in the medical device arena can collectively use the findings of this report to help make public health a central focus of their activities, along with the work on policies, tools and innovations of the WHO Global Initiative for Health Technologies.
WX 147 Equipment and supplies --- Cost of Illness --- Research --- Equipment and Supplies --- Biomedical Engineering --- Public Health --- Equipment and supplies --- Standards --- Diseases --- Costs
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WA 30 Social, economic, and environmental factors in public health (General) --- Physician-Patient Relations --- Health Services Accessibility --- Health Behavior --- Socioeconomic Factors --- Dental Caries --- Pediculus --- Academic Dissertations --- (DAI-0573) sciences and engineering -- health sciences -- health sciences -- public health --- Sciences and engineering --- health sciences --- public health --- public health. --- Health sciences --- Public health.
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Hygiene. Public health. Protection --- Economic policy and planning (general) --- United States --- W 74 Medical economics. Health care costs (General) --- Medical Care --- Health Care Costs --- Quality control --- Cost-effectiveness analysis --- Competition. --- Medical care --- Value analysis (Cost control) --- Delivery of Health Care --- Economic Competition --- Quality of Health Care --- Cost control. --- Cost effectiveness. --- Quality control. --- economics --- Value analysis (Cost control). --- Competition --- Value engineering --- Cost control --- Cost effectiveness --- Industrial engineering --- Medical care, Cost of --- Competition (Economics) --- Competitiveness (Economics) --- Economic competition --- Commerce --- Conglomerate corporations --- Covenants not to compete --- Industrial concentration --- Monopolies --- Open price system --- Supply and demand --- Trusts, Industrial --- Economic aspects --- Economics --- #SBIB:316.334.3M50 --- Organisatie van de gezondheidszorg: algemeen, beleid --- United States of America
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"Equally useful as a reference for individuals interested in the analysis of lifetime data and as a text for advanced students, Statistical Models and Methods for Lifetime Data, Second Edition provides broad coverage of the area without concentrating on any single field of application. Extensive illustrations and examples drawn from engineering and the biomedical sciences provide readers with a clear understanding of key concepts."--Jacket.
Mathematical statistics --- QA 276 .L328 Mathematical statistics --- Failure time data analysis --- Survival analysis (Biometry) --- AA / International- internationaal --- 303.0 --- 304.0 --- Statistische technieken in econometrie. Wiskundige statistiek (algemene werken en handboeken). --- Zuivere statistische analyse (algemene naslagwerken). Tijdreeksen. --- Failure time data analysis. --- Analysis, Failure time data --- Data analysis, Failure time --- Failure analysis (Engineering) --- Competing risks --- Analysis, Survival (Biometry) --- Survivorship analysis (Biometry) --- Biometry --- Survival analysis (Biometry). --- Statistische technieken in econometrie. Wiskundige statistiek (algemene werken en handboeken) --- Zuivere statistische analyse (algemene naslagwerken). Tijdreeksen --- Statistique
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Graphics are great for exploring data, but how can they be used for looking at the large datasets that are commonplace to-day? This book shows how to look at ways of visualizing large datasets, whether large in numbers of cases or large in numbers of variables or large in both. Data visualization is useful for data cleaning, exploring data, identifying trends and clusters, spotting local patterns, evaluating modeling output, and presenting results. It is essential for exploratory data analysis and data mining. Data analysts, statisticians, computer scientists-indeed anyone who has to explore a large dataset of their own-should benefit from reading this book. New approaches to graphics are needed to visualize the information in large datasets and most of the innovations described in this book are developments of standard graphics. There are considerable advantages in extending displays which are well-known and well-tried, both in understanding how best to make use of them in your work and in presenting results to others. It should also make the book readily accessible for readers who already have a little experience of drawing statistical graphics. All ideas are illustrated with displays from analyses of real datasets and the authors emphasize the importance of interpreting displays effectively. Graphics should be drawn to convey information and the book includes many insightful examples. Antony Unwin holds the Chair of Computer Oriented Statistics and Data Analysis at the University of Augsburg. He has been involved in developing visualization software for twenty years. Martin Theus is a Senior Researcher at the University of Augsburg, has worked in industry and research in both Germany and the USA, and is the author of the visualization software Mondrian. Heike Hofmann is Assistant Professor of Statistics at Iowa State University. She wrote the software MANET and has also cooperated in the development of the GGobi software.
Artificial intelligence. Robotics. Simulation. Graphics --- Information systems --- QA 276.3 Graphic methods --- Computational Science & Engineering --- Computational Statistics --- Computer Imaging, Graphics & Vision --- Computer Science --- Statistics --- Computer graphics. --- Statistique --- Infographie --- Graphic methods. --- Méthodes graphiques --- Computer graphics --- Graphic methods --- Statistics -- Graphic methods. --- Mathematics --- Physical Sciences & Mathematics --- Mathematical Statistics --- Méthodes graphiques --- EPUB-LIV-FT LIVSTATI SPRINGER-B --- Automatic drafting --- Graphic data processing --- Graphics, Computer --- Diagrams, Statistical --- Statistical diagrams --- Mathematics. --- Operations research. --- Decision making. --- Data mining. --- Visualization. --- Computer software. --- Statistics. --- Mathematical Software. --- Statistical Theory and Methods. --- Data Mining and Knowledge Discovery. --- Operation Research/Decision Theory. --- Computer Graphics. --- Computer art --- Graphic arts --- Electronic data processing --- Engineering graphics --- Image processing --- Statistical analysis --- Statistical data --- Statistical methods --- Statistical science --- Econometrics --- Software, Computer --- Computer systems --- Visualisation --- Imagery (Psychology) --- Imagination --- Visual perception --- Algorithmic knowledge discovery --- Factual data analysis --- KDD (Information retrieval) --- Knowledge discovery in data --- Knowledge discovery in databases --- Mining, Data --- Database searching --- Deciding --- Decision (Psychology) --- Decision analysis --- Decision processes --- Making decisions --- Management --- Management decisions --- Choice (Psychology) --- Problem solving --- Operational analysis --- Operational research --- Industrial engineering --- Management science --- Research --- System theory --- Math --- Science --- Digital techniques --- Decision making --- Curve fitting --- Mathematical statistics. --- Operations Research/Decision Theory. --- Statistical inference --- Statistics, Mathematical --- Probabilities --- Sampling (Statistics) --- Statistics . --- Statistics - Graphic methods
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Skillfully done, research can be the solid cornerstone of your term paper (or dissertation, essay, or article); inadequately executed, it can cause your whole project to crumble and fall. Yet essential as research is to the ultimate success of your work, performing it is not an innate talent. The precepts, steps, and skills of solid research are readily acquired if you spend some time with The Craft of Research before you start on your outlines and thesis statements. Written by three distinguished professors in 1995, published by the University of Chicago, and winner of the 1995-96 Critics' Choice Award, The Craft of Research teaches how to plan, carry out, and report on research for any field and at any level. Aimed at assisting student researchers, from raw beginners to accomplished graduate and professional students, the book shows how to choose a topic, plan and organize research, and how to draft and revise a report of findings such that a convincing solution is offered to a significant problem.The Craft of Research is more than just another instruction manual getting you from topic to outline to notes to report. Recognizing that good research is rarely a simple, sequential procedure, but is instead a complex and intricate process, it discusses the subtle ways in which asking questions about your topic can influence how you draft your report, how a quality introduction can send you back to the library, and how the process of drafting can highlight flaws in your argument that need to be addressed. Clear and explicit, sophisticated and practical, The Craft of Research encourages high standards of scholarly achievement, and spells out the steps by which to get there. --Stephanie Gold --This text refers to the Hardcover edition.
Science --- Research --- Technical writing --- Recherche --- Sciences --- Methodology --- Méthodologie --- Art d'écrire --- 303.8 --- 001.81 --- Organisatie en leiding van sociaal onderzoek --- Techniek van de intellectuele arbeid --- Technical writing. --- Methodology. --- 001.81 Techniek van de intellectuele arbeid --- 303.8 Organisatie en leiding van sociaal onderzoek --- Méthodologie --- Art d'écrire --- Engineering --- Scientific writing --- Technology --- Authorship --- Communication of technical information --- THESES ET ECRITS ACADEMIQUES --- RECHERCHE DOCUMENTAIRE --- REDACTION --- GUIDES, MANUELS, ETC. --- Databases, Research projects --- Education Research --- HM 571 Study and Teaching. Research -- General works --- Research methods --- Research Report
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* Contains additional discussion and examples on left truncation as well as material on more general censoring and truncation patterns. * Introduces the martingale and counting process formulation swil lbe in a new chapter. * Develops multivariate failure time data in a separate chapter and extends the material on Markov and semi Markov formulations. * Presents new examples and applications of data analysis.
Mathematical statistics --- QA 276 .K215 Mathematical statistics --- Failure time data analysis --- Survival analysis (Biometry) --- Regression analysis --- AA / International- internationaal --- 303.0 --- 304.0 --- 519.5 --- Analysis, Regression --- Linear regression --- Regression modeling --- Multivariate analysis --- Structural equation modeling --- Analysis, Survival (Biometry) --- Survivorship analysis (Biometry) --- Biometry --- Analysis, Failure time data --- Data analysis, Failure time --- Failure analysis (Engineering) --- Competing risks --- Statistische technieken in econometrie. Wiskundige statistiek (algemene werken en handboeken). --- Zuivere statistische analyse (algemene naslagwerken). Tijdreeksen. --- Failure time data analysis. --- Regression analysis. --- Survival analysis (Biometry). --- Statistische technieken in econometrie. Wiskundige statistiek (algemene werken en handboeken) --- Zuivere statistische analyse (algemene naslagwerken). Tijdreeksen
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#SBIB:303H4 --- #SBIB:303H520 --- 681.3*E --- AA / International- internationaal --- 654 --- 10.02.d --- 10.03.c --- 681.3*E Data --- Data --- Informatica in de sociale wetenschappen --- Methoden sociale wetenschappen: techniek van de analyse, algemeen --- Informatieverwerking. Bureautica. --- Statistieken Demografische statistieken --- Actuariaat Constructie (Sterfte)tafels --- Failure time data analysis --- Survival analysis (Biometry) --- Analysis, Survival (Biometry) --- Survivorship analysis (Biometry) --- Biometry --- Analysis, Failure time data --- Data analysis, Failure time --- Failure analysis (Engineering) --- Mathematical statistics --- Competing risks --- Data processing --- Statistieken ; Demografische statistieken --- Actuariaat ; Constructie (Sterfte)tafels --- Informatieverwerking. Bureautica --- SAS (Computer file) --- Statistical analysis system --- SAS system --- Programming --- Survival Analysis --- Automatic Data Processing --- Data processing. --- SAS (Computer file). --- Failure time data analysis - Data processing --- Survival analysis (Biometry) - Data processing --- QA 76.755 - Computer Software. Handbook --- SAS --- Electronic data processing
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Technological innovation is deeply woven into the fabric of American culture, and is no less a basic feature of American health care. Medical technology saves lives and relieves suffering, and is enormously popular with the public, profitable for doctors, and a source of great wealth for industry. Yet its costs are rising at a dangerously unsustainable rate. The control of technology costs poses a terrible ethical and policy dilemma. How can we deny people what they may need to live and flourish? Yet is it not also harmful to let rising costs strangle our health care system, eventually harming everyone? In Taming the Beloved Beast, esteemed medical ethicist Daniel Callahan confronts this dilemma head-on. He argues that we can't escape it by organizational changes alone. Nothing less than a fundamental transformation of our thinking about health care is needed to achieve lasting and economically sustainable reform. The technology bubble, he contends, is beginning to burst. Callahan weighs the ethical arguments for and against limiting the use of medical technologies, and he argues that reining in health care costs requires us to change entrenched values about progress and technological innovation. Taming the Beloved Beast shows that the cost crisis is as great as that of the uninsured. Only a government-regulated universal health care system can offer the hope of managing technology and making it affordable for all.
Medical care, Cost of --United States. --- Medical technology --Economic aspects --United States. --- Medical care, Cost of --- Medical technology --- Health Care Costs --- Biomedical Technology --- United States --- Economics --- Insurance --- Delivery of Health Care --- Technology --- North America --- Costs and Cost Analysis --- Financing, Organized --- Social Sciences --- Americas --- Health Care Quality, Access, and Evaluation --- Anthropology, Education, Sociology and Social Phenomena --- Technology, Industry, and Agriculture --- Geographic Locations --- Health Care Economics and Organizations --- Technology, Industry, Agriculture --- Health Care --- Geographicals --- Medical Economics --- Public Health --- Health & Biological Sciences --- Economic aspects --- Health care technology --- Health technology --- Biomedical Technologies --- Technology, Biomedical --- Technology, Health --- Technology, Health Care --- Health Care Technology --- Health Technology --- Biomedical Engineering --- Medical Informatics --- Costs, Medical Care --- Health Costs --- Healthcare Costs --- Medical Care Costs --- Treatment Costs --- Cost, Health --- Cost, Health Care --- Cost, Healthcare --- Cost, Medical Care --- Cost, Treatment --- Costs, Health --- Costs, Health Care --- Costs, Healthcare --- Costs, Treatment --- Health Care Cost --- Health Cost --- Healthcare Cost --- Medical Care Cost --- Treatment Cost --- Health Expenditures --- Indemnity --- Insurance Premiums --- Insurance Premium --- Premium, Insurance --- Premiums, Insurance --- economics --- E-books --- Cost of medical care --- Health care costs --- Health care expenditures --- Medical care --- Medical costs --- Medical expenses --- Medical service, Cost of --- Medicine --- Medical economics --- Medical savings accounts --- Assurance (Insurance) --- Coverage, Insurance --- Indemnity insurance --- Insurance coverage --- Insurance industry --- Insurance protection --- Mutual insurance --- Underwriting --- Finance --- Costs --- Ethics --- Technology Assessment, Biomedical --- W 82 Biomedical technology (General)
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